2017 Feb;62(1):28-33. doi: 10.1177/0036933016689006. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a recently defined inflammatory central nervous system (CNS) disorder, prominently involving the brainstem and in particular the pons.
Marked clinical and radiological corticosteroid responsiveness was observed in CLIPPERS (23/23), and clinical worsening occurred in all 12 CLIPPERS cases when corticosteroids were discontinued. fevers or sweats or meningism) These lesions histologically demonstrate a lymphocytic perivascular inflammatory pattern MRI is the imaging modality of choice for the assessment of patients with suspected brainstem pathology. There may be a slight male predilection 1. This paper presents a brief literature review on chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome.
2018 Jan 1;141(1):e6. 2014 Mar;175(3):385-96. doi: 10.1111/cei.12204.Hou X, Wang X, Xie B, Lin W, Liu J, Ma D, Zhang HL.Medicine (Baltimore).
Unable to load your collection due to an error Epub 2020 Jan 10.Liu XH, Jin F, Zhang M, Liu MX, Wang T, Pan BJ, Zhang L.BMC Neurol. Clipboard, Search History, and several other advanced features are temporarily unavailable. Whether CLIPPERS represents an independent, actual new disorder or a syndrome that includes aetiologically heterogeneous diseases and/or their prestages remains a debated and not finally clarified issue. Unable to load your delegates due to an error 2018 Oct 1;141(10):e75. 2010 Sep;133(9):2626-34. doi: 10.1093/brain/awq164. Print 2019 Nov.
in This paper presents a brief literature review on chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome. 2018 Feb 1;141(2):e13.
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The appearance of CLIPPERS on MRI is fairly unique, characterized by multiple punctate, patchy and linear regions of contrast enhancement relatively confined to the pons Despite striking post contrast appearances, there is relatively little edema or positive mass effect.
Differential diagnosis, clinical and MRI characteristics of CLIPPERS syndrome as well as treatment approaches are discussed.
As withdrawal of GCS treatment results commonly in disease exacerbation, long-term immunosuppressive therapy appears to be mandatory for sustained improvement. Clinical and neuroimaging data were reviewed by three neurologists to confirm CLIPPERS by consensus agreement. Pathogenesis of CLIPPERS remains poorly understood, and the nosological position of CLIPPERS has still to be established. 2014 Mar;175(3):385-96. doi: 10.1111/cei.12204.Pittock SJ, Debruyne J, Krecke KN, Giannini C, van den Ameele J, De Herdt V, McKeon A, Fealey RD, Weinshenker BG, Aksamit AJ, Krueger BR, Shuster EA, Keegan BM.Brain. A rare cause of dizziness and gait ataxia clippers syndrome cureus chronic lymphocytic inflammation with pontine cureus chronic lymphocytic inflammation with pontine characteristic pontine predominant mri characteristics of clippers. Clinicians and radiologists should be aware of this condition and its differential diagnoses, given that CLIPPERS constitutes a treatable condition and that patients may benefit from an early introduction of GCS ensued by long-term immunosuppression. eCollection 2020 Jun.Bot JCJ, Mazzai L, Hagenbeek RE, Ingala S, van Oosten B, Sanchez-Aliaga E, Barkhof F.Neuroradiology. doi: 10.1093/brain/awx299.Brain. Published by Oxford University Press on behalf of the Guarantors of Brain.
Following its initial description, the salient features of CLIPPERS have been confirmed and expanded upon, but the lack of formalized diagnostic criteria has led to … Lesions may extend into the basal ganglia or the cervico-thoracal medulla. COVID-19 is an emerging, rapidly evolving situation. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an uncommon and only recently described disorder characterized by infiltration of the brain by inflammatory cells.
Unable to load your delegates due to an error Entité décrite pour la première fois en 2010.
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